Today, The Leona M. and Harry B. Helmsley Charitable Trust announces seven new grants to support research aimed at helping people with type 1 diabetes (T1D) more safely incorporate exercise into their...
Seven new projects supported by Helmsley’s T1D Exercise Initiative (T1-DEXI) will develop and evaluate new education platforms and modules, diabetes device algorithm improvements, new insulins, interventions, and other factors that may affect exercise
NEW YORK: Today, The Leona M. and Harry B. Helmsley Charitable Trust announces seven new grants to support research aimed at helping people with type 1 diabetes (T1D) more safely incorporate exercise into their lives. This support, totaling more than $12 million, is a major stride forward in trying to build knowledge in this important area of unmet need for T1D.
Currently, people with T1D must use trial-and-error to keep their blood sugar under control when exercising, because the impact of exercise can be unpredictable. Technologies like continuous glucose monitors (CGMs) can help, but many people with T1D avoid exercise altogether because of the risk of low blood sugar during or after, which can be dangerous. More research and solutions are urgently needed to ease the burden of exercise with T1D management.
“Glycemic variability and exercise in T1D remains a challenge that current diabetes technology solutions are still not equipped to manage adequately, and available clinical guidelines are too complex or hard to follow in the real-world,” said Deniz Dalton, a program officer in Helmsley’s T1D Program. “The initial work with T1-DEXI data offers an incredible opportunity to expand research in this area. The wide range of projects we’re funding will bring us closer to giving people with T1D the tools they need to manage exercise more easily and safely.”
The T1D Exercise Initiative (T1-DEXI) data sets provide baseline information for the T1D community to move beyond trial-and-error. It is the largest observational exercise study in people with T1D, conducted by the Jaeb Center for Health Research (JCHR) in collaboration with other T1D investigators. The data sets are publicly available through Vivli, a data-sharing platform that hosts information on a variety of health conditions. Currently, T1-DEXI data is the most requested data set on the platform surpassing other data set requests to date.
Building on the learnings from the T1-DEXI data, Helmsley launched an RFP in late 2022 seeking research projects that can provide people with T1D, and their healthcare providers, practical management solutions for T1D and exercise. Projects will evaluate new education platforms and modules, diabetes device algorithm improvements, new insulins with automated insulin delivery systems, alternatives to carbohydrate intervention in managing exercise and T1D, and other factors that may impact exercise, such as menstruation.
The seven funded projects are:
About The Leona M. and Harry B. Helmsley Charitable Trust
The Leona M. and Harry B. Helmsley Charitable Trust aspires to improve lives by supporting exceptional efforts in the U.S. and around the world in health and select place-based initiatives. Since beginning active grantmaking in 2008, Helmsley has committed more than $4 billion for a wide range of charitable purposes. The Helmsley Type 1 Diabetes (T1D) Program is the largest private foundation funder in the world with a focus on T1D, with more than $1 billion to date committed to transform the trajectory of the disease and to accelerate access to 21st century care, everywhere. For more information on Helmsley and its programs, visit helmsleytrust.org.
Fonte: Business Wire
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